Implantable Microsystems for Brain Cancer Therapy

Brain tumors—particularly aggressive forms like glioblastoma—remain among the most treatment-resistant cancers, with recurrence nearly inevitable and survival rates devastatingly low. Inoperable tumors deepen the urgent need for innovative, precise, and durable therapeutic approaches.

We are developing a disruptive, minimally invasive drug delivery microsystem designed for spatially precise, programmable treatment of brain tumors. A network of ultra-thin, implantable microcatheters delivers therapeutics directly into the tumor and its infiltrative margins. Integrated micropumps, embedded sensors, and wireless control enable dynamic, sustained release—overcoming the limitations of systemic therapy. Custom-designed for each patient, this system enables volumetric, localized treatment while minimizing off-target toxicity. It holds potential not only for resectable tumors but also for deep, inoperable lesions, transforming care for patients with the worst prognoses. Beyond brain cancer, the platform could extend to other neurological conditions such as epilepsy and Parkinson's disease.